Resumo

S. MOSCOSO, Manolete. From the mind to the cell: the impact of stress on Psiconeuroimmunoendocrinology. Liberabit [online]. 2009, vol.15, n.2, pp.143-152. ISSN 1729-4827.

This article reviews the biopsicosocial model provided by Engel and the first studies in the field of psychoneuroimmunoendocrinology published by Solomon during the 60's and Ader during the 70's. it is pointed out that advances in medical technology and laboratory facilitated the beginning of studies in this field during the 80's. Extensive data reports conclusive evidence of the interconnections between the brain, the nervous, endocrine and immune systems and the development of disease. We discussed the emotional and physiological responses to stress as described by Lazarus, Cannon, and Selye. A new vision about stress is presented, taking into account the behavioral response to stress, life style, and chronic stress. Finally, we discussed briefly about the negative impact of chronic stress on health.

Palavras-chave : Stress; Brain; Immune system; Endocrine System.

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