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Journal of Human Growth and Development

versão impressa ISSN 0104-1282

Resumo

BERTOLI, Ciro João; LEONE, Claudio; JUNQUEIRA, Virginia B.V.  e  CARRAZZA, Francisco Roque. Mother's and newborn's plasmatic concentration of micronutrients at the moment of childbirth. Rev. bras. crescimento desenvolv. hum. [online]. 2010, vol.20, n.2, pp. 270-281. ISSN 0104-1282.

Cross sectional study of a sequential convenience sample of 73 non smokers' pregnant women with uncomplicated pregnancies and their normal newborns. The aim of the study was to compare plasmatic concentrations of retinol, β-carotene, licopen and α-tocopherol between mothers and their infants. Blood was obtained from parturient and umbilical cord for micronutrient analysis. HPLC was used for retinol, α-carotene, licopen and α-tocopherol analysis. Atomic absorption spectrophotometry was used for copper measurements. The sample was divided into 2 groups: group 1, with 38 women that had received vitamin and mineral supplementation during the last gestational trimester and group 2, with 35 women who have had no supplementation. Statistic comparison used Student t test or Wilcoxon test (alpha = 0.05). The groups of mothers were similar regarding age, parity, BMI and ingestion (low) of calories and micronutrients. The newborn groups had no differences according to sex, head circumference, weight and length. Plasmatic concentrations in group 1 of mothers were greater for retinol (p = 0.0034) and α-tocopherol (p = 0.0279). β-carotene, licopen and cupper showed no differences between the groups at mothers. In both newborn groups concentration of retinol, α-tocopherol and copper were quite similar and there was no clearly detectable licopen and 2 carotene. In both, retinol, α-tocopherol and cupper showed larger concentration in mothers than in newborns (respectively p = 0.0003 and p = 0.0001). The conclusion is that newborn concentrations were systematically smaller than their mothers', independently of ingestion or supple-mentation during pregnancy.

Palavras-chave : retinol (vitamin A); β-caroten; licopen; α-tocopherol (vitamin E); cupper; newborns; pregnant women.

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