Abstract

SILVA, Juciara da C.; RIBEIRO, Miriam O.; SANTOS, Déborah M. dos  and  PENATTI, Carlos Alberto A.. Review and update of ultrasonic vocalization in animals: Correlation with autism spectrum disorder experimental models?. Psicol. teor. prat. [online]. 2020, vol.22, n.2, pp. 179-197. ISSN 1516-3687.  http://dx.doi.org/10.5935/1980-6906/psicologia.v22n2p83-104.

The ability to understand and to communicate is essential for the adapted social and cultural development of children. Autism spectrum disorders (ASD) are characterized by social interaction deficiencies in the verbal language domain and may incur in repetitive, stereotyped, and restricted gestural behaviors. Regarding animal models in ASD, many studies focus on gene expression, cortical neuronal migration and cell maturation, and neural network deficits. However, very few studies directly link animal oral communication and gene expression in cortical areas of language. The object of our study aimed to review and to correlate genes involved in ASD and those related to ultrasonic communication in animal model studies of language-based social behavior at the PubMed database. The PubMed search yielded 25 selected papers. Some findings showed critical genes, which modulate several aspects of verbal communication. Most of these genes can be markers of communication deficits.

Keywords : communication; ultrasound vocalization; ASD; genetics; neurodevelopment.

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