Introduction:

Chronic Kidney Disease-Mineral and Bone Disease is one of the main complications of individuals on hemodialysis.

Objective:

this research aims to analyze the correlations of the laboratory components of Chronic Kidney Disease-Mineral and Bone Disease with clinical, anthropometric and laboratory factors of individuals on hemodialysis.

Methods:

this is a cross-sectional study with 790 patients on hemodialysis, in southeastern Brazil. Chronic Kidney Disease- Mineral and Bone Disease was evaluated according to specific laboratory diagnostic criteria already defined in the literature. Assessment was carried out regarding the existence of a linear correlation between the dependent and independent variables. References used: r < 0.4 (weak correlation); r ≥ 0.4 and < 0.6 (moderate correlation); r ≥ 0.6 (strong correlation). The Significance level adopted was 5%.

Results:

parathyroid hormone and duration of renal replacement therapy showed a moderate positive correlation with each other (r 0.582, p <0.001). Phosphorus levels had a moderate positive correlation with potassium (r 0.556, p 0.020) and negative correlation with age (r -0.413, p 0.036). 25-hydroxyvitamin D levels had a positive correlation with adductor pollicis muscle thickness (r 0.602, p 0.018) and right hand grip strength (r 0.402, p <0.001), and a negative correlation with tricipital skinfold (r -0.600, p 0.020) and corrected arm muscle area (r -0.769, p 0.024). Ionic calcium levels had a strong positive correlation with duration of renal replacement therapy (r 0.961, p 0.015) and a strong negative correlation with Body Mass Index (r -0.82, p 0.046).

Conclusion:

all laboratory elements of Chronic Kidney Disease- Mineral and Bone Disease showed important correlations with clinical, anthropometric and laboratory components of individuals on hemodialysis.

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