Resumo

LOPES JUNIOR, Luís Carlos et al. WHO Global Initiative for Childhood Cancer: progress and challenges for Cure All Framework. J. Hum. Growth Dev. [online]. 2025, vol.35, n.3, pp.350-357.  Epub 10-Abr-2026. ISSN 0104-1282.  https://doi.org/10.36311/jhgd.v35.18282.

Childhood cancer accounts for between 1% and 4% of global cancer cases, reaching up to 10% in low- and middle-income countries (LMICs), where more than 90% of cases occur and where significant inequalities in diagnosis and access to treatment persist. While up to 80% of children can be cured in high-income countries, mortality is almost four times higher in LMICs, driven by diagnostic delays, advanced stages at presentation, a lack of evidence-based protocols, a shortage of specialized professionals, and high rates of treatment abandonment. Given this scenario, childhood cancer should be prioritized on the public health agenda, as it is a cost-effective intervention and aligned with the fight against chronic noncommunicable diseases. To reduce disparities, in 2018 the WHO launched the Global Initiative for Childhood Cancer, which seeks to increase global survival to 60% by 2030, guided by the CureAll Framework, structured around strengthening specialized services, universal coverage, quality protocols, and robust monitoring systems, supported by advocacy, financing, and integrated governance.

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